Cell-type decomposition of spatial transcriptomics spots

Estimate the cell-type proportions in each spot of simulated spatial transcriptomics data, given a single-cell reference.

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	1	+{
	2	+ "domain": "life-health",
	3	+ "topics": [
	4	+ "single-cell"
	5	+ ],
	6	+ "type": "algorithm",
	7	+ "benchmark": {
	8	+ "task": "Estimate per-spot cell-type proportions from a single-cell reference",
	9	+ "metric": {
	10	+ "name": "Overall: mean control-scaled metric score (0–1)",
	11	+ "better": "higher"
	12	+ },
	13	+ "baseline": {
	14	+ "name": "Best on Open Problems v1.0.0 (Cell2location)",
	15	+ "score": 0.853826
	16	+ }
	17	+ },
	18	+ "source": {
	19	+ "key": "openproblems-bio",
	20	+ "name": "Open Problems in Single-Cell Analysis",
	21	+ "url": "https://openproblems.bio/benchmarks/spatial_decomposition",
	22	+ "id": "spatial_decomposition",
	23	+ "curator": "Open Problems in Single-Cell Analysis consortium",
	24	+ "poser": "Alma Andersson, Giovanni Palla et al.",
	25	+ "status": "open",
	26	+ "as_of": "2026-10-20",
	27	+ "catalog": "0521c19bbd38"
	28	+ }
	29	+}